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Published: May, 2014 | Pages:
253 | Publisher: Global Markets Direct
Industry: Pharmaceutical | Report Format: Electronic (PDF)
Amgen Inc. - Product Pipeline Review - 2014 Summary Global Markets Direct's, 'Amgen Inc. - Product Pipeline Review - 2014', provides an overview of the Amgen Inc.'s pharmaceutical research and development focus. This report provides comprehensive information on the current therapeutic developmental pipeline of Amgen Inc.'s, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides brief overview of Amgen Inc. including business description, key information and facts, and its locations and subsidiaries - The report reviews current pipeline of Amgen Inc.'s human therapeutic division and enlists all their major and minor projects - The report features product description and descriptive mechanism of action for key pipeline products along with the product's developmental history and major milestones - Special feature on out-licensed and partnered product portfolio - The report summarizes all the dormant and discontinued pipeline projects - Latest company statement - Latest news and deals relating to the Amgen Inc.'s pipeline products Reasons to buy - Evaluate Amgen Inc.'s strategic position with total access to detailed information on its product pipeline - Assess the growth potential of Amgen Inc. in its therapy areas of focus - Identify new drug targets and therapeutic classes in the Amgen Inc.'s R&D portfolio and develop key strategic initiatives to reinforce pipeline in those areas - Exploit in-licensing opportunities by identifying windows of opportunity to fill portfolio gaps - Develop strategic initiatives by understanding the focus areas of Amgen Inc. and exploit collaboration and partnership opportunities - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Plan mergers and acquisitions effectively by identifying the most promising pipeline of Amgen Inc. - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Explore the dormant and discontinued projects of Amgen Inc. and identify potential opportunities in those areas - Avoid Intellectual Property Rights related issues
Table of Contents Table of Contents 2 List of Tables 6 List of Figures 6 Amgen Inc. Snapshot 7 Amgen Inc. Overview 7 Key Information 7 Key Facts 7 Amgen Inc. - Research and Development Overview 8 Key Therapeutic Areas 8 Amgen Inc. - Pipeline Review 17 Pipeline Products by Stage of Development 17 Pipeline Products - Monotherapy 18 Pipeline Products - Partnered Products 19 Pipeline Products - Out-Licensed Products 21 Amgen Inc. - Pipeline Products Glance 25 Amgen Inc. - Late Stage Pipeline Products 25 Amgen Inc. - Clinical Stage Pipeline Products 29 Amgen Inc. - Early Stage Pipeline Products 33 Amgen Inc. - Unknown Stage Pipeline Products 37 Amgen Inc. - Drug Profiles 38 darbepoetin alfa 38 denosumab 40 panitumumab 43 pegfilgrastim 46 romiplostim 48 adalimumab biosimilar 50 bevacizumab biosimilar 51 bixalomer 52 blinatumomab 54 brodalumab 57 cinacalcet hydrochloride 59 evolocumab 61 ivabradine 63 rilotumumab 65 romosozumab 67 talimogene laherparepvec 69 trastuzumab biosimilar 71 trebananib 72 velcalcetide 75 abrilumab 77 AMG-139 79 AMG-151 80 AMG-157 82 AMG-334 83 AMG-337 84 fulranumab 85 ganitumab 87 omecamtiv mecarbil 90 AMG-232 92 AMG-172 93 AMG-208 95 AMG-282 96 AMG-319 97 AMG-333 98 AMG-357 99 AMG-557 100 AMG-581 102 AMG-595 103 AMG-729 105 AMG-780 106 AMG-811 107 AMG-820 109 AMG-876 110 AMG-900 111 mogamulizumab 113 MT-111 115 MT-112 117 solitomab 119 Activin Type IIB Receptor Antagonist for Cancer Cachexia 121 AM-1638 122 AM-6226 123 AM-8553 124 AMG-161 125 AMG-1694 126 AMG-3969 127 AMG-511 128 AMG-925 129 Amgen-3 130 Amgen-4 131 Beta-Secretase 1 Inhibitors for Alzheimer Disease 132 Biaryl Amide 133 BiTE Antibody Targetting CD33 134 BiTE For Solid Tumors 135 Calcimimetic-18 for Secondary Hyperparathyroidism 136 cetuximab 137 cetuximab biosimilar 138 Dual PI3K Beta/Delta Inhibitors for Rheumatoid Arthritis And Inflammation 139 EP2 Antagonists for Alzheimer Disease 140 First Generation Diacylglycerol Acyltransferase Inhibitor for Obesity Dyslipidemia And Type 2 Diabetes 141 GPR142 Agonists for Type 2 Diabetes 142 Human Beta Secretase Inhibitor 143 Keto-benzimidazoles 144 MCSP BiTE Antibody 145 morpholinone-27 146 MT-204 147 Multiple Myeloma BiTE 148 Phosphoinositide Kinase Inhibitor for Inflammation And Oncology 149 Recombinant Fc-FGF21 150 rituximab biosimilar 151 Second Generation Diacylglycerol Acyltransferase Inhibitor for Obesity Dyslipidemia And Type 2 Diabetes 152 Small Molecule to Agonize GPR119 for Undisclosed Indication 153 Triazine Sulfonamide 154 AA-71 155 Cdc7 Kinase Inhibitors Program 156 Drugs for Inflammatory Bowel Disease 157 Morpholinone-10 158 Morpholinone-16 159 Small Molecule Inhibits Tankyrase for Cancer 160 Small Molecule Targeting GPR119 161 Amgen Inc. - Pipeline Analysis 162 Amgen Inc. - Pipeline Products by Target 162 Amgen Inc. - Pipeline Products by Route of Administration 168 Amgen Inc. - Pipeline Products by Molecule Type 169 Amgen Inc. - Pipeline Products by Mechanism of Action 171 Amgen Inc. - Recent Pipeline Updates 178 Amgen Inc. - Dormant Projects 224 Amgen Inc. - Discontinued Pipeline Products 229 Discontinued Pipeline Product Profiles 229 Amgen Inc. - Company Statement 235 Amgen Inc. - Locations And Subsidiaries 238 Head Office 238 Other Locations & Subsidiaries 238 Amgen Inc. - Key Manufacturing Facilities 245 Appendix 246 Methodology 246 Coverage 246 Secondary Research 246 Primary Research 246 Expert Panel Validation 246 Contact Us 247 Disclaimer 247
List of Tables Amgen Inc., Key Information 13 Amgen Inc., Key Facts 13 Amgen Inc. - Pipeline by Indication, 2014 15 Amgen Inc. - Pipeline by Stage of Development, 2014 23 Amgen Inc. - Monotherapy Products in Pipeline, 2014 24 Amgen Inc. - Partnered Products in Pipeline, 2014 25 Amgen Inc. - Partnered Products/ Combination Treatment Modalities, 2014 26 Amgen Inc. - Out-Licensed Products in Pipeline, 2014 27 Amgen Inc. - Out-Licensed Products/ Combination Treatment Modalities, 2014 28 Amgen Inc. - Pre-Registration, 2014 31 Amgen Inc. - Filing rejected/Withdrawn, 2014 32 Amgen Inc. - Phase III, 2014 33 Amgen Inc. - Phase II, 2014 35 Amgen Inc. - Phase I, 2014 37 Amgen Inc. - Preclinical, 2014 39 Amgen Inc. - Discovery, 2014 42 Amgen Inc. - Unknown, 2014 43 Amgen Inc. - Pipeline by Target, 2014 169 Amgen Inc. - Pipeline by Route of Administration, 2014 174 Amgen Inc. - Pipeline by Molecule Type, 2014 176 Amgen Inc. - Pipeline Products by Mechanism of Action, 2014 178 Amgen Inc. - Recent Pipeline Updates, 2014 184 Amgen Inc. - Dormant Developmental Projects,2014 230 Amgen Inc. - Discontinued Pipeline Products, 2014 235 Amgen Inc., Other Locations 244 Amgen Inc., Subsidiaries 247 Amgen Inc., Key Manufacturing Facilities 251
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