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Published: Aug, 2015 | Pages:
56 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)
Alcoholic Hepatitis - Pipeline Review, H1 2015 Summary Global Markets Direct’s, ‘Alcoholic Hepatitis - Pipeline Review, H1 2015’, provides an overview of the Alcoholic Hepatitis’s therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Alcoholic Hepatitis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Alcoholic Hepatitis and special features on late-stage and discontinued projects. Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of Alcoholic Hepatitis - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Alcoholic Hepatitis and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Alcoholic Hepatitis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Alcoholic Hepatitis pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for Alcoholic Hepatitis - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding Alcoholic Hepatitis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 4 List of Figures 4 Introduction 5 Global Markets Direct Report Coverage 5 Alcoholic Hepatitis Overview 6 Therapeutics Development 7 Pipeline Products for Alcoholic Hepatitis - Overview 7 Pipeline Products for Alcoholic Hepatitis - Comparative Analysis 8 Alcoholic Hepatitis - Therapeutics under Development by Companies 9 Alcoholic Hepatitis - Therapeutics under Investigation by Universities/Institutes 10 Alcoholic Hepatitis - Pipeline Products Glance 11 Clinical Stage Products 11 Early Stage Products 12 Alcoholic Hepatitis - Products under Development by Companies 13 Alcoholic Hepatitis - Products under Investigation by Universities/Institutes 14 Alcoholic Hepatitis - Companies Involved in Therapeutics Development 15 Alfact Innovation 15 Conatus Pharmaceuticals Inc. 16 Generon (Shanghai) Corporation Ltd. 17 Immuron Limited 18 Intercept Pharmaceuticals, Inc. 19 Oncozyme Pharma Inc. 20 Alcoholic Hepatitis - Therapeutics Assessment 21 Assessment by Monotherapy Products 21 Assessment by Target 22 Assessment by Mechanism of Action 24 Assessment by Route of Administration 26 Assessment by Molecule Type 28 Drug Profiles 30 ALF-5755 - Drug Profile 30 Product Description 30 Mechanism of Action 30 R&D Progress 30 emricasan - Drug Profile 32 Product Description 32 Mechanism of Action 32 R&D Progress 32 F-652 - Drug Profile 34 Product Description 34 Mechanism of Action 34 R&D Progress 34 IMM-124E - Drug Profile 35 Product Description 35 Mechanism of Action 35 R&D Progress 35 obeticholic acid - Drug Profile 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 Oligonucleotide to Inhibit miRNA-155 for Alcoholic Liver Disease - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 pentamidine isethionate - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 Alcoholic Hepatitis - Recent Pipeline Updates 44 Alcoholic Hepatitis - Dormant Projects 52 Alcoholic Hepatitis - Product Development Milestones 53 Featured News & Press Releases 53 Sep 11, 2013: Conatus Pharmaceuticals Initiates Phase 2b Trial of Emricasan in Acute-on-Chronic Liver Failure Patients 53 Sep 10, 2013: Conatus Pharmaceuticals' Emricasan Dosed in First Patient in Mayo Clinic Phase 2 Trial in Severe Alcoholic Hepatitis Population 53 Appendix 55 Methodology 55 Coverage 55 Secondary Research 55 Primary Research 55 Expert Panel Validation 55 Contact Us 55 Disclaimer 56
List of Tables Number of Products under Development for Alcoholic Hepatitis, H1 2015 7 Number of Products under Development for Alcoholic Hepatitis - Comparative Analysis, H1 2015 8 Number of Products under Development by Companies, H1 2015 9 Number of Products under Investigation by Universities/Institutes, H1 2015 10 Comparative Analysis by Clinical Stage Development, H1 2015 11 Comparative Analysis by Early Stage Development, H1 2015 12 Products under Development by Companies, H1 2015 13 Products under Investigation by Universities/Institutes, H1 2015 14 Alcoholic Hepatitis - Pipeline by Alfact Innovation, H1 2015 15 Alcoholic Hepatitis - Pipeline by Conatus Pharmaceuticals Inc., H1 2015 16 Alcoholic Hepatitis - Pipeline by Generon (Shanghai) Corporation Ltd., H1 2015 17 Alcoholic Hepatitis - Pipeline by Immuron Limited, H1 2015 18 Alcoholic Hepatitis - Pipeline by Intercept Pharmaceuticals, Inc., H1 2015 19 Alcoholic Hepatitis - Pipeline by Oncozyme Pharma Inc., H1 2015 20 Assessment by Monotherapy Products, H1 2015 21 Number of Products by Stage and Target, H1 2015 23 Number of Products by Stage and Mechanism of Action, H1 2015 25 Number of Products by Stage and Route of Administration, H1 2015 27 Number of Products by Stage and Molecule Type, H1 2015 29 Alcoholic Hepatitis Therapeutics - Recent Pipeline Updates, H1 2015 44 Alcoholic Hepatitis - Dormant Projects, H1 2015 52
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