Alcohol Addiction - Pipeline Review, H1 2015

Published: Jan, 2015 | Pages: 119 | Publisher: Global Markets Direct
Industry: Pharmaceuticals & Healthcare | Report Format: Electronic (PDF)

Alcohol Addiction - Pipeline Review, H1 2015

Summary

Global Markets Direct's, 'Alcohol Addiction - Pipeline Review, H1 2015', provides an overview of the Alcohol Addiction's therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Alcohol Addiction, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Alcohol Addiction and special features on late-stage and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Alcohol Addiction
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities 
- The report reviews key players involved in the therapeutics development for Alcohol Addiction and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects 
- A review of the Alcohol Addiction products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Alcohol Addiction pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons To Buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Alcohol Addiction
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Alcohol Addiction pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

 Table of Contents
Table of Contents 2
List of Tables 7
List of Figures 8
Introduction 9
Global Markets Direct Report Coverage 9
Alcohol Addiction Overview 10
Therapeutics Development 11
Pipeline Products for Alcohol Addiction - Overview 11
Pipeline Products for Alcohol Addiction - Comparative Analysis 12
Alcohol Addiction - Therapeutics under Development by Companies 13
Alcohol Addiction - Therapeutics under Investigation by Universities/Institutes 16
Alcohol Addiction - Pipeline Products Glance 17
Late Stage Products 17
Clinical Stage Products 18
Early Stage Products 19
Alcohol Addiction - Products under Development by Companies 20
Alcohol Addiction - Products under Investigation by Universities/Institutes 22
Alcohol Addiction - Companies Involved in Therapeutics Development 23
AbbVie Inc. 23
Addex Therapeutics Ltd 24
Adial Pharmaceuticals, LLC 25
Astraea Therapeutics, LLC 26
AstraZeneca PLC 27
Bionex Pharmaceuticals LLC 28
Curemark, LLC 29
D&A Pharma SAS 30
Eli Lilly and Company 31
Euthymics Bioscience, Inc. 32
Foresee Pharmaceuticals, LLC 33
Heptares Therapeutics Ltd. 34
Johnson & Johnson 35
Kyorin Pharmaceutical Co., Ltd. 36
Lohocla Research Corporation 37
Omeros Corporation 38
Pfizer Inc. 39
SK Biopharmaceuticals Co., Ltd. 40
Sun Pharma Advanced Research Company Ltd. 41
Tekmira Pharmaceuticals Corp. 42
Tonix Pharmaceuticals Holding Corp. 43
VM Discovery, Inc. 44
Zynerba Pharmaceuticals, Inc. 45
Alcohol Addiction - Therapeutics Assessment 46
Assessment by Monotherapy Products 46
Assessment by Combination Products 47
Assessment by Target 48
Assessment by Mechanism of Action 50
Assessment by Route of Administration 52
Assessment by Molecule Type 54
Drug Profiles 56
(disulfiram + selegiline) - Drug Profile 56
Product Description 56
Mechanism of Action 56
R&D Progress 56
(topiramate + ondansetron hydrochloride) - Drug Profile 57
Product Description 57
Mechanism of Action 57
R&D Progress 57
ABT-436 - Drug Profile 58
Product Description 58
Mechanism of Action 58
R&D Progress 58
ADX-71441 - Drug Profile 59
Product Description 59
Mechanism of Action 59
R&D Progress 59
amitifadine - Drug Profile 60
Product Description 60
Mechanism of Action 60
R&D Progress 60
Antisense Gene Therapy for Alcoholism - Drug Profile 62
Product Description 62
Mechanism of Action 62
R&D Progress 62
baclofen ER - Drug Profile 63
Product Description 63
Mechanism of Action 63
R&D Progress 63
carisbamate - Drug Profile 64
Product Description 64
Mechanism of Action 64
R&D Progress 64
CM-1212 - Drug Profile 66
Product Description 66
Mechanism of Action 66
R&D Progress 66
Drug to Inhibit Triple Reuptake for Alcohol Dependence - Drug Profile 67
Product Description 67
Mechanism of Action 67
R&D Progress 67
Drugs to Activate HAT for CNS Disorders - Drug Profile 68
Product Description 68
Mechanism of Action 68
R&D Progress 68
Drugs to Inhibit Histone Deacetylase for CNS Disorders - Drug Profile 69
Product Description 69
Mechanism of Action 69
R&D Progress 69
Drugs to Target HAT and HDAC for Alcohol Addiction and Anxiety Disorders - Drug Profile 70
Product Description 70
Mechanism of Action 70
R&D Progress 70
FP-007 - Drug Profile 71
Product Description 71
Mechanism of Action 71
R&D Progress 71
GET-73 - Drug Profile 72
Product Description 72
Mechanism of Action 72
R&D Progress 72
ibudilast - Drug Profile 73
Product Description 73
Mechanism of Action 73
R&D Progress 73
JNJ-31020028 - Drug Profile 75
Product Description 75
Mechanism of Action 75
R&D Progress 75
JNJ-5234801 - Drug Profile 76
Product Description 76
Mechanism of Action 76
R&D Progress 76
LY-2940094 - Drug Profile 77
Product Description 77
Mechanism of Action 77
R&D Progress 77
naltrexone - Drug Profile 78
Product Description 78
Mechanism of Action 78
R&D Progress 78
naltrexone - Drug Profile 79
Product Description 79
Mechanism of Action 79
R&D Progress 79
OMS-405 - Drug Profile 80
Product Description 80
Mechanism of Action 80
R&D Progress 80
OMS-527 - Drug Profile 81
Product Description 81
Mechanism of Action 81
R&D Progress 81
ondansetron hydrochloride - Drug Profile 82
Product Description 82
Mechanism of Action 82
R&D Progress 82
PF-04457845 - Drug Profile 83
Product Description 83
Mechanism of Action 83
R&D Progress 83
saracatinib difumarate - Drug Profile 84
Product Description 84
Mechanism of Action 84
R&D Progress 84
SLV-330 - Drug Profile 86
Product Description 86
Mechanism of Action 86
R&D Progress 86
Small Molecule for Central Nervous System - Drug Profile 87
Product Description 87
Mechanism of Action 87
R&D Progress 87
Small Molecule to Antagonize Ghrelin for Alcoholism - Drug Profile 89
Product Description 89
Mechanism of Action 89
R&D Progress 89
Small Molecule to Antagonize Mu Opioid Receptor for Drug Abuse and Alcohol Addiction - Drug Profile 90
Product Description 90
Mechanism of Action 90
R&D Progress 90
Small Molecule to Antagonize Orexin 1 for Addiction and Compulsive Disorders - Drug Profile 91
Product Description 91
Mechanism of Action 91
R&D Progress 91
Small Molecules to Agonize NOP for Pain - Drug Profile 92
Product Description 92
Mechanism of Action 92
R&D Progress 92
sodium oxybate IR - Drug Profile 94
Product Description 94
Mechanism of Action 94
R&D Progress 94
TKM-ALDH2 - Drug Profile 95
Product Description 95
Mechanism of Action 95
R&D Progress 95
VMD-2202 - Drug Profile 96
Product Description 96
Mechanism of Action 96
R&D Progress 96
Alcohol Addiction - Recent Pipeline Updates 97
Alcohol Addiction - Dormant Projects 106
Alcohol Addiction - Discontinued Products 108
Alcohol Addiction - Product Development Milestones 109
Featured News & Press Releases 109
Jan 07, 2015: Addex and NIAAA Enter Collaboration to Evaluate ADX71441 in Alcohol Use Disorder 109
Apr 30, 2014: ADial Pharmaceuticals Announces Issuance of First U.S. Patent 109
Nov 04, 2013: Clinical Trial Indicates Gabapentin Is Safe and Effective for Treating Alcohol Dependence 110
Oct 10, 2013: Tekmira Provides Corporate Update on TKM-ALDH2 112
Aug 25, 2013: National Institute on Alcohol Abuse and Alcoholism Funds New UCLA Clinical Trial of MediciNova's MN-166 in Treating Alcoholism 113
Aug 12, 2013: ADial Pharmaceuticals Announces Publication of Study on AD04 for the Treatment of Patients With Alcohol Use Disorder 113
Aug 09, 2013: Curemark wins patent for CM-1212 to treat drug, alcohol addiction 114
May 21, 2013: Addex Validates Potential Efficacy Biomarker For Phase I Trial Of ADX71441 115
Apr 30, 2013: Addex Therapeutics Reports ADX71441 Reduces Alcohol Intake In Preclinical Model Of Chronic Alcohol Dependence 115
Apr 18, 2013: ADial Pharma Announces Agreement With FDA For Phase III Trial Of AD04 For Alcohol Use Disorder In Patients Of Targeted Genotypes 116
Appendix 118
Methodology 118
Coverage 118
Secondary Research 118
Primary Research 118
Expert Panel Validation 118
Contact Us 118
Disclaimer 119

List of Tables
Number of Products under Development for Alcohol Addiction, H1 2015 11
Number of Products under Development for Alcohol Addiction - Comparative Analysis, H1 2015 12
Number of Products under Development by Companies, H1 2015 14
Number of Products under Development by Companies, H1 2015 (Contd..1) 15
Number of Products under Investigation by Universities/Institutes, H1 2015 16
Comparative Analysis by Late Stage Development, H1 2015 17
Comparative Analysis by Clinical Stage Development, H1 2015 18
Comparative Analysis by Early Stage Development, H1 2015 19
Products under Development by Companies, H1 2015 20
Products under Development by Companies, H1 2015 (Contd..1) 21
Products under Investigation by Universities/Institutes, H1 2015 22
Alcohol Addiction - Pipeline by AbbVie Inc., H1 2015 23
Alcohol Addiction - Pipeline by Addex Therapeutics Ltd, H1 2015 24
Alcohol Addiction - Pipeline by Adial Pharmaceuticals, LLC, H1 2015 25
Alcohol Addiction - Pipeline by Astraea Therapeutics, LLC, H1 2015 26
Alcohol Addiction - Pipeline by AstraZeneca PLC, H1 2015 27
Alcohol Addiction - Pipeline by Bionex Pharmaceuticals LLC, H1 2015 28
Alcohol Addiction - Pipeline by Curemark, LLC, H1 2015 29
Alcohol Addiction - Pipeline by D&A Pharma SAS, H1 2015 30
Alcohol Addiction - Pipeline by Eli Lilly and Company, H1 2015 31
Alcohol Addiction - Pipeline by Euthymics Bioscience, Inc., H1 2015 32
Alcohol Addiction - Pipeline by Foresee Pharmaceuticals, LLC, H1 2015 33
Alcohol Addiction - Pipeline by Heptares Therapeutics Ltd., H1 2015 34
Alcohol Addiction - Pipeline by Johnson & Johnson, H1 2015 35
Alcohol Addiction - Pipeline by Kyorin Pharmaceutical Co., Ltd., H1 2015 36
Alcohol Addiction - Pipeline by Lohocla Research Corporation, H1 2015 37
Alcohol Addiction - Pipeline by Omeros Corporation, H1 2015 38
Alcohol Addiction - Pipeline by Pfizer Inc., H1 2015 39
Alcohol Addiction - Pipeline by SK Biopharmaceuticals Co., Ltd., H1 2015 40
Alcohol Addiction - Pipeline by Sun Pharma Advanced Research Company Ltd., H1 2015 41
Alcohol Addiction - Pipeline by Tekmira Pharmaceuticals Corp., H1 2015 42
Alcohol Addiction - Pipeline by Tonix Pharmaceuticals Holding Corp., H1 2015 43
Alcohol Addiction - Pipeline by VM Discovery, Inc., H1 2015 44
Alcohol Addiction - Pipeline by Zynerba Pharmaceuticals, Inc., H1 2015 45
Assessment by Monotherapy Products, H1 2015 46
Assessment by Combination Products, H1 2015 47
Number of Products by Stage and Target, H1 2015 49
Number of Products by Stage and Mechanism of Action, H1 2015 51
Number of Products by Stage and Route of Administration, H1 2015 53
Number of Products by Stage and Molecule Type, H1 2015 55
Alcohol Addiction Therapeutics - Recent Pipeline Updates, H1 2015 97
Alcohol Addiction - Dormant Projects, H1 2015 106
Alcohol Addiction - Dormant Projects (Contd..1), H1 2015 107
Alcohol Addiction - Discontinued Products, H1 2015 108