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Published: Aug, 2014 | Pages:
60 | Publisher: Global Markets Direct
Industry: Healthcare | Report Format: Electronic (PDF)
African Trypanosomiasis - Pipeline Review, H2 2014 Summary Global Markets Direct's, 'African Trypanosomiasis - Pipeline Review, H2 2014', provides an overview of the African Trypanosomiasis's therapeutic pipeline. This report provides comprehensive information on the therapeutic development for African Trypanosomiasis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for African Trypanosomiasis and special features on late-stage and discontinued projects. Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - The report provides a snapshot of the global therapeutic landscape of African Trypanosomiasis - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for African Trypanosomiasis and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the African Trypanosomiasis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the African Trypanosomiasis pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Reasons to buy - Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage - Develop strategic initiatives by understanding the focus areas of leading companies - Identify and understand important and diverse types of therapeutics under development for African Trypanosomiasis - Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline - Devise corrective measures for pipeline projects by understanding African Trypanosomiasis pipeline depth and focus of Indication therapeutics - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents Table of Contents 2 List of Tables 5 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 African Trypanosomiasis Overview 7 Therapeutics Development 8 Pipeline Products for African Trypanosomiasis - Overview 8 Pipeline Products for African Trypanosomiasis - Comparative Analysis 9 African Trypanosomiasis - Therapeutics under Development by Companies 10 African Trypanosomiasis - Therapeutics under Investigation by Universities/Institutes 11 African Trypanosomiasis - Pipeline Products Glance 12 Clinical Stage Products 12 Early Stage Products 13 African Trypanosomiasis - Products under Development by Companies 14 African Trypanosomiasis - Products under Investigation by Universities/Institutes 15 African Trypanosomiasis - Companies Involved in Therapeutics Development 16 Sanofi 16 D-Pharm Ltd. 17 Scynexis, Inc. 18 Anacor Pharmaceuticals, Inc. 19 African Trypanosomiasis - Therapeutics Assessment 20 Assessment by Monotherapy Products 20 Assessment by Target 21 Assessment by Mechanism of Action 23 Assessment by Route of Administration 25 Assessment by Molecule Type 27 Drug Profiles 29 fexinidazole - Drug Profile 29 Product Description 29 Mechanism of Action 29 R&D Progress 29 AN-5568 - Drug Profile 31 Product Description 31 Mechanism of Action 31 R&D Progress 31 DP-460 - Drug Profile 33 Product Description 33 Mechanism of Action 33 R&D Progress 33 DP-b99 - Drug Profile 34 Product Description 34 Mechanism of Action 34 R&D Progress 34 AN-3520 - Drug Profile 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 SCYX-6759 - Drug Profile 38 Product Description 38 Mechanism of Action 38 R&D Progress 38 DDD-85646 - Drug Profile 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 Oxabarole Backup Compound - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 NVPBEZ-235 - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 African Sleeping Sickness Program - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 Small Molecules to Inhibit Leucyl-tRNA Synthetase (LeuRS) for Human African Trypanosomiasis - Drug Profile 43 Product Description 43 Mechanism of Action 43 R&D Progress 43 Small Molecules to Inhibit Nitroreductase for Chagas Disease and African Trypanosomiasis - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 Small Molecules to Inhibit Bcl-2 for Infectious Disease and Oncology - Drug Profile 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 Peptides for African Sleeping Sickness - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 Small Molecules for Sleeping Sickness - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 Small Molecules for Malaria and African Trypanosomiasis - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Small Molecules for Leishmaniasis, Chagas disease and HAT - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 Small Molecules for Protozoal Infections - Drug Profile 50 Product Description 50 Mechanism of Action 50 R&D Progress 50 African Trypanosomiasis - Recent Pipeline Updates 51 African Trypanosomiasis - Dormant Projects 54 African Trypanosomiasis - Discontinued Products 55 African Trypanosomiasis - Product Development Milestones 56 Featured News & Press Releases 56 Aug 19, 2013: Positive Results for D-Pharm's Investigational Drugs in Models of Human African Trypanosomiasis and Malaria 56 Mar 12, 2012: Anacor Announces Commencement Of Phase I Clinical Trials Of Boron-Based Compound For Sleeping Sickness 56 Jun 28, 2011: Anacor Pharmaceuticals Partnership Advances New Drug Candidate To Combat Sleeping Sickness 57 Appendix 59 Methodology 59 Coverage 59 Secondary Research 59 Primary Research 59 Expert Panel Validation 59 Contact Us 60 Disclaimer 60
List of Tables Number of Products under Development for African Trypanosomiasis, H2 2014 8 Number of Products under Development for African Trypanosomiasis - Comparative Analysis, H2 2014 9 Number of Products under Development by Companies, H2 2014 10 Number of Products under Investigation by Universities/Institutes, H2 2014 11 Comparative Analysis by Clinical Stage Development, H2 2014 12 Comparative Analysis by Early Stage Development, H2 2014 13 Products under Development by Companies, H2 2014 14 Products under Investigation by Universities/Institutes, H2 2014 15 African Trypanosomiasis - Pipeline by Sanofi, H2 2014 16 African Trypanosomiasis - Pipeline by D-Pharm Ltd., H2 2014 17 African Trypanosomiasis - Pipeline by Scynexis, Inc., H2 2014 18 African Trypanosomiasis - Pipeline by Anacor Pharmaceuticals, Inc., H2 2014 19 Assessment by Monotherapy Products, H2 2014 20 Number of Products by Stage and Target, H2 2014 22 Number of Products by Stage and Mechanism of Action, H2 2014 24 Number of Products by Stage and Route of Administration, H2 2014 26 Number of Products by Stage and Molecule Type, H2 2014 28 African Trypanosomiasis Therapeutics - Recent Pipeline Updates, H2 2014 51 African Trypanosomiasis - Dormant Projects, H2 2014 54 African Trypanosomiasis - Discontinued Products, H2 2014 55
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